GEO series
Evaluate of transcriptomic alternation with Berberine and RPS6KB1 depletion that sensitizes prostate tumors to radiation
GSE245798
Homo sapiens
Expression profiling by high throughput sequencing
21 samples
2025/06/04
GPL24676GPL18573
Summary
Transcriptomic analysis of androgen responsive LNCaP cells depleted (RPS6KB1 KO), overexpressing for RPS6KB1 (RPS6KB1 OE) and treated with berberine (24h treatment with 5 microg/ml prior to radiation) in combination with radiation. Results provide insight into the role of RPS6KB1 in response to radiation.
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Paper (PMID 38925361) ↗
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