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Effect of HSD52 overexpression on gene expression in LN229 glioma cells

GSE246649 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/05/29 Platform GPL24676
Summary
In order to study the effect of HSD52 on the malignant progression and chemotherapy resistance of glioma, we examined the effect of HSD52 on the gene expression of brain glioma cells. We used lentiviral constructs to establish the LN229 cell line overexpressing HSD52. We subsequently performed gene expression profiling using RNA-seq data obtained from control LN229 cells and HSD52-overexpressing LN229 cells.
Published in
A novel nuclear RNA HSD52 scaffolding NONO/SFPQ complex modulates DNA damage repair to facilitate temozolomide resistance
Sun N, Chen Q, Chen H et al. · Neuro-oncology 2025 · PMID 39673809 · doi:10.1093/neuonc/noae272
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Also filed as BioProject PRJNA1034052 and SRA study SRP469441. Searching any of these in the dataset finder brings you back here.

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