RB modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions [RNA-Seq]
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- RB loss modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactionsNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE246944_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1035136 and SRA study SRP470003. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE266412 RB modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions [HiChIP] 4 samples shares cohesin-dependent, enhancer-promoter, organization, interactions, regulating, modulates, chromatin
- GSE216549 Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of androgen receptor in prostate cancer cells (LNCaP RNA-seq) 24 samples shares interactions, chromatin, rna-seq
- GSE263641 CTCF depletion uncouples the role of enhancer-promoter interactions and higher-order chromatin hubs in gene regulation during cellular differentiation. 137 samples shares enhancer-promoter, interactions, chromatin
- GSE235711 Immune-Epithelial Interactions and Tissue Remodeling in the Inflammatory Respiratory Nasal Tract [scRNA-seq] 20 samples shares interactions, rna-seq
- GSE300791 Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal Cord [scRNA-seq] 20 samples shares organization, rna-seq
- GSE293428 Mapping Endothelial-Macrophage Interactions in Diabetic Vasculature: Role of TREM2 in Vascular Inflammation and Ischemic Response [scRNA-Seq] 18 samples shares interactions, rna-seq
- GSE279180 Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions [snRNA-seq] 16 samples shares interactions, rna-seq
- GSE290659 MYC-FACT Interactions Drive Z-DNA Formation to Modulate Transcriptional Dynamics [RNA-seq CC & CL] 16 samples shares interactions, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.