Productively HIV-1 infected and bystander primary human CD4+ T-cells
Non-coding RNA profiling · human · 18 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Downregulation of miRNA-26a by HIV-1 Enhances CD59 Expression and Packaging, Impacting Virus Susceptibility to Antibody-Dependent Complement-Mediated LysisViruses · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE247196_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1036599 and SRA study SRP470561. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7885040 lymphocytes, GFP-, Donor 146M (mRNA)
- GSM7885041 lymphocytes, GFP+, Donor 146M (mRNA)
- GSM7885042 lymphocytes, uninfected, Donor 146M (mRNA)
- GSM7885043 lymphocytes, GFP-, Donor 173M (mRNA)
- GSM7885044 lymphocytes, GFP+, Donor 173M (mRNA)
- GSM7885045 lymphocytes, uninfected, Donor 173M (mRNA)
- GSM7885046 lymphocytes, GFP-, Donor 206F (mRNA)
- GSM7885047 lymphocytes, GFP+, Donor 206F (mRNA)
- GSM7885048 lymphocytes, uninfected, Donor 206F (mRNA)
- GSM7885073 lymphocytes, GFP-, Donor 146M (miRNA)
- GSM7885074 lymphocytes, GFP+, Donor 146M (miRNA)
- GSM7885075 lymphocytes, uninfected, Donor 146M (miRNA)
- GSM7885076 lymphocytes, GFP-, Donor 173M (miRNA)
- GSM7885077 lymphocytes, GFP+, Donor 173M (miRNA)
- GSM7885078 lymphocytes, uninfected, Donor 173M (miRNA)
- GSM7885079 lymphocytes, GFP-, Donor 206F (miRNA)
- GSM7885080 lymphocytes, GFP+, Donor 206F (miRNA)
- GSM7885081 lymphocytes, uninfected, Donor 206F (miRNA)
- GSE328010 RNA sequencing of naïve, activated and HIV-1 infected CD4+ T cells 9 samples shares hiv-1, cd4, infected
- GSE329693 Microbiome-Derived Metabolites Shape CD4⁺ T-Cell Differentiation and Immune Aging in Chronic HIV-1 Infection [RNA-Seq] 36 samples shares hiv-1, cd4
- GSE319139 The HIV-1 Vpr R77Q mutant alters host apoptotic gene regulation in CD4+ T cells 33 samples shares hiv-1, cd4
- GSE280563 HIV-1 m6A methylome investigation by m6A-SAC-seq [CD4+ T cells] 12 samples shares hiv-1, cd4
- GSE314342 Genome-scale perturb-seq in primary human CD4+ T cells reveals genes regulating T cell programs and human immune traits. 577 samples shares cd4, primary
- GSE216688 Identification of a transcription factor network that regulates anti-TNF mediated IL-10 expression in human CD4+ T-cells 16 samples shares cd4, t-cells
- GSE299348 Single-cell epigenetic, transcriptional, protein, and TCR states of HIV-1-infected cells in gut 117 samples shares hiv-1, infected
- GSE342431 Transcriptomic effects of combined AZD4573 and SMAP-2 treatment in resting and anti-CD3/CD28-activated primary human CD4+ T cells 12 samples shares cd4, primary
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.