Investigation of gene expression in glioma cell lines
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Genome-wide CRISPR-Cas9 screens identify BCL family members as modulators of response to regorafenib in experimental gliomaNeuro-oncology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE247498_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1038797 and SRA study SRP471282. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7890779 LN18 (biol rep1)
- GSM7890780 LN18 (biol rep2)
- GSM7890781 LN18 (biol rep3)
- GSM7890782 LN229 (biol rep1)
- GSM7890783 LN229 (biol rep2)
- GSM7890784 LN229 (biol rep3)
- GSM7890785 LNZ308 (biol rep1)
- GSM7890786 LNZ308 (biol rep2)
- GSM7890787 LNZ308 (biol rep3)
- GSM7890788 T98G (biol rep1)
- GSM7890789 T98G (biol rep2)
- GSM7890790 T98G (biol rep3)
- GSM7890791 GS-2 (biol rep1)
- GSM7890792 GS-2 (biol rep2)
- GSM7890793 GS-2 (biol rep3)
- GSM7890794 GS-9 (biol rep1)
- GSM7890795 GS-9 (biol rep2)
- GSM7890796 GS-9 (biol rep3)
- GSE306559 Regulation of temozolomide resistance by m6A mRNA methylation in glioma cell lines 24 samples shares glioma, lines
- GSE288929 Baseline Gene Expression in Human Derived Cell Lines 180 samples shares lines
- GSE298581 Global gene expression response to PPARG inhibition in three urothelial cancer cell lines 48 samples shares lines
- GSE330891 Spatial and cell type specific molecular genetic investigations of inflammatory myopathies with selective perifascicular injury. 301 samples shares investigation
- GSE273995 Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer cell lines and isogenic models 36 samples shares lines
- GSE274006 Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer cell lines and isogenic models [isogenic models] 33 samples shares lines
- GSE251807 Investigation of gene expression changes in normal human dermal fibroblasts after exposure to bone marrow mesenchymal stromal cell secretome 32 samples shares investigation
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares lines
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.