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Single-cell transcriptomic atlas of cystic echinococcosis reveals diversity roles of small extracellular vesicles derived from Echinococcus granulosus during liver infection

GSE247521 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/10/14 Platform GPL23479
Summary
Cystic echinococcosis acts as a public health threat worldwide and causes considerable economic loss. Liver is the main paraistic organ during infection, whereas the the regulatory roles of PSC-sEV for liver cells remains unclear. In this study, we sequenced and analyzed single-cell transcriptomic of liver targeted by PSC -sEV, to illuminate the cross-talk between protoscoleces and host cells.
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Direct links to NCBI, no account and no request form: the whole study as GSE247521_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1039284 and SRA study SRP471349. Searching any of these in the dataset finder brings you back here.

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