GEO series
RNA-seq of osteogenesis following siRNA depletion of SERPINA3
GSE247528
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2024/08/05
GPL18573
Summary
SERPINA3 knockdown was observed to reduce cartilage pellet size following differentiation of mesenchymal stem cells (MSCs) to chondrocytes. To additionally understand any effects on the osteogenesis transcriptome, RNA-sequencing was conducted on primary MSCs depleted of SERPINA3 with siRNA and compared to cells transfected with a siRNA control over a 7 day period.
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Paper (PMID 39097037) ↗
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