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H3K27Ac ChIP-seq to investigate the role of ACLY pathway in senescent cells.

GSE247604 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2024/06/26 Platform GPL18573
Summary
H3K27Ac ChIP-seq analysis revealed that the inhibition of ACLY pathway supressed the expression of proinflammatory SASP
Published in
Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
Etoh K, Araki H, Koga T et al. · Cell reports 2024 · PMID 39043191 · doi:10.1016/j.celrep.2024.114496
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Also filed as BioProject PRJNA1039804 and SRA study SRP471616. Searching any of these in the dataset finder brings you back here.

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