Simulated Lunar Microgravity Transiently Arrests Growth and Induces Osteocyte-Chondrocyte Lineage Differentiation in Human Wharton’s jelly stem cells.
RNA-seq (gene expression) · human · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 26 samples: 26 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Simulated lunar microgravity transiently arrests growth and induces osteocyte-chondrocyte lineage differentiation in human Wharton's jelly stem cellsNPJ microgravity · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248366_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1043607 and SRA study SRP473245. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 26 sample titles: 26 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7912166 W005M_D3_ExptCtrl
- GSM7912167 W005M_D6_ExptCtrl
- GSM7912168 W012M_D3_ExptCtrl
- GSM7912169 W013F_D3_ExptCtrl
- GSM7912170 W033F_D3_ExptCtrl
- GSM7912171 W033F_D6_ExptCtrl
- GSM7912172 W037M_D3_ExptCtrl
- GSM7912173 W037M_D6_ExptCtrl
- GSM7912174 W040F_D3_ExptCtrl
- GSM7912175 W040F_D6_ExptCtrl
- GSM7912176 W042M_D3_ExptCtrl
- GSM7912177 W042M_D6_ExptCtrl
- GSM7912178 W043F_D6_ExptCtrl
- GSM7912179 W005M_D3_suG
- GSM7912180 W012M_D3_suG
- GSM7912181 W013F_D3_suG
- GSM7912182 W033F_D3_suG
- GSM7912183 W037M_D3_suG
- GSM7912184 W040F_D3_suG
- GSM7912185 W042M_D3_suG
- GSM7912186 W005M_D6_post_suG
- GSM7912187 W033F_D6_post_suG
- GSM7912188 W037M_D6_post_suG
- GSM7912189 W040F_D6_post_suG
- GSM7912190 W042M_D6_post_suG
- GSM7912191 W043F_D6_post_suG
- GSE301964 T Cell Transcriptome Alterations in Healthy Volunteers Exposed to Three Weeks of Simulated Microgravity 50 samples shares microgravity, simulated
- GSE231848 Simulated microgravity recapitulates early molecular events and sex differences of knee osteoarthritis 24 samples shares microgravity, simulated
- GSE271642 Effects of Simulated Microgravity on Colorectal Cancer Organoids Growth and Drug Response 8 samples shares microgravity, simulated
- GSE226395 Gene expression profile at of motor neurons under simulated microgravity (SMG) and normal gravity(NG) 6 samples shares microgravity, simulated
- GSE255750 Simulated Microgravity Impairs Human NK Cell Cytotoxic Activity Against Space Radiation-Relevant Leukemic Cells 4 samples shares microgravity, simulated
- GSE304580 Single-nucleus RNA-seq analysis of YAP5SA-induced human trophoblast organoids cultured under simulated microgravity 2 samples shares microgravity, simulated
- GSE306469 Single-nucleus RNA-seq analysis of extravillous trophoblast differentiation from human trophoblast organoids cultured under simulated microgravity 2 samples shares microgravity, simulated
- GSE303893 Single-nuclus RNA sequencing of stem cell-derived human trophoblast organoids cultured under simulated microgravity 1 samples shares microgravity, simulated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.