GEO series
PIK3CA and KRAS codon-specific mutations differentially toggle pathway activity and alter sensitivity to inavolisib (GDC-0077)
GSE248412
Homo sapiens
Expression profiling by high throughput sequencing
26 samples
2025/06/15
GPL24676GPL18573GPL20301
Summary
To explore the single and combinatorial effect of MEK and PI3KCA inhibitors in CRC lines with PIK3CA/KRAS mutations, we used the MULTI-seq CMOs to perform a highly multiplexed single-cell RNA-seq.
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Paper (PMID 40625102) ↗
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