Comparison of gene expression by activated T-cells that express NKG2D-based CARs
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Solid tumor immunotherapy using NKG2D-based adaptor CAR T cellsCell reports. Medicine · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249511_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1049416 and SRA study SRP476179. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 17 more — browse all 17 samples with per-sample file links →
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- GSE292969 Effect of CCS1477 treatment on gene expression in NRF2-activated lung cancer cells 18 samples shares activated, express
- GSE266852 Comparison of differential gene expression in blood PBMCs from healthy controls, patients with rheumatoid arthritis,and patients with lupus using single-cell transcriptome sequencing analysis. 10 samples shares comparison, express
- GSE330761 CD25 expression marks an activated mast cell population in human nasal polyposis 25 samples shares activated, express
- GSE301269 Comparison of expression profiles of Control and CDDO-Im treatment microglia under IFN-gamma or Amyloid beta stimulation 24 samples shares comparison, express
- GSE230683 Effect of treatment with Levamisole 1 mM on activated human T-cells 12 samples shares activated, t-cells
- GSE10086 Expression profiling of V600E BRAF and RTK-activated cells upon MEK inhibition 36 samples shares activated, express
- GSE216688 Identification of a transcription factor network that regulates anti-TNF mediated IL-10 expression in human CD4+ T-cells 16 samples shares t-cells, express
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.