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Bulk RNA-seq of human kidney organids in different culture conditions

GSE250468 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/03/03 Platform GPL30173
Summary
To date strategies aiming to modulate cell to extracellular matrix (ECM) interactions during organoid derivation remain largely unexplored. Here, renal decellularized extracellular matrix (dECM) hydrogels have been fabricated from porcine renal cortex as new biomaterials to enrich cell-to-ECM crosstalk during the onset of kidney organoid differentiationfrom human pluripotent stem cells (hPSCs).Renal dECM derived hydrogels are used in combination with hPSC-derived renal progenitor cellsto define new approaches for 2D and 3D kidney organoid differentiation.
Published in
Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis
Garreta E, Moya-Rull D, Marco A et al. · Advanced materials (Deerfield Beach, Fla.) 2024 · PMID 38762768 · doi:10.1002/adma.202400306
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Also filed as BioProject PRJNA1054116 and SRA study SRP478661. Searching any of these in the dataset finder brings you back here.

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