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Genome-scale analysis of aberrant DNA methylation in colorectal cancer

GSE25062 Homo sapiens Methylation profiling by array 154 samples Submitted 2011/06/03 Platform GPL8490
Summary
To characterize DNA methylation-based subgroups in colorectal cancer, we performed genome-scale DNA methylation profiling of 125 colorectal tumor samples and 29 histologically normal-adjacent colonic tissue samples using the Illumina Infinium DNA methylation assay, which assesses the DNA methylation status of 27,578 CpG sites located at the promoter regions of 14,495 protein-coding genes. We identified four DNA methylation-based subgroups of CRC using model-based cluster analyses. Each subtype shows characteristic genetic and clinical features, indicating that they represent biologically distinct subgroups.
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Direct links to NCBI, no account and no request form: the whole study as GSE25062_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 154 samples.

Also filed as BioProject PRJNA134727. Searching any of these in the dataset finder brings you back here.

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