GEO series
The effect of STING knockout on gene expression in DMXAA-induced BMDMs and BMDCs
GSE252101
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2024/08/14
GPL24247
Summary
Myeloid-derived STING has been recognized to play a vital role in mediating the development of colitis. We here report that in BMDMs and BMDCs, knockout of STING inhibited pathways related to IL-12/23 production and IL-12 signaling, inflammation, and the maturation and activation of macrophages and DCs.
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Paper (PMID 39113810) ↗
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