GEO series
High-throughput transcriptomics of water extracts detects reductions in biological activity with water treatment processes
GSE252117
Homo sapiens
Expression profiling by high throughput sequencing
510 samples
2024/03/05
GPL16791
Summary
The presence of numerous chemical contaminants from industrial, agricultural, and pharmaceutical sources in water supplies poses a potential risk to human and ecological health. Current chemical analyses suffer from limitations including chemical coverage and high cost, and broad-coverage in vitro assays such as transcriptomics may further improve water quality monitoring by assessing a large range of possible effects. Here, we used high-throughput transcriptomics to assess the activity induced by field-derived water extracts in MCF7 breast carcinoma cells.
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Paper (PMID 38235672) ↗
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