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DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

GSE252442 Mus musculus (mouse) RNA-seq (gene expression) 134 samples Submitted 2024/12/04 Platform GPL24676Platform GPL24247
At a glance

RNA-seq (gene expression) · mouse · 134 samples

What it is
RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
Organism
Mus musculus (mouse)
Samples
134 samples: 92 distinct titles, 24 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAsCell reports · 2025
SuperSeries — this record groups several sub-series.
Summary (written by the submitters)
This SuperSeries is composed of the SubSeries listed below.
Published in
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs
Miao W, Porter DF, Siprashvili Z et al. · Cell reports 2025 · PMID 39764852 · doi:10.1016/j.celrep.2024.115174
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE252442_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.

Also filed as BioProject PRJNA1060656 and SRA study SRP480826. Searching any of these in the dataset finder brings you back here.

Study design
92 distinct titles, 24 of them repeated
DDX50 STAU1 Glc dms ×4 Exp119 DDX50 Prog KC ×3 Exp119 DDX50 L gluc KC ×3 Exp119 DDX50 H gluc KC ×3 Exp115 DDX50 Prog KC ×3 Exp115 DDX50 L gluc KC ×3 Exp115 DDX50 H gluc KC ×3 No DMS dms ×3 +16 more

How we read this: Read from 134 sample titles: 92 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

+ 94 more — browse all 134 samples with per-sample file links →

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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.