GEO series
Influence of GPR35 deficiency on the ileal and macrophage transcriptome
GSE252926
Mus musculus
Expression profiling by high throughput sequencing
20 samples
2025/02/07
GPL17021GPL13112
Summary
Mutations in GPR35 (G protein coupled receptor 35) are linked to ulcerative colitis and primary sclerosing cholangitis. How GPR35, which interacts with the Na/K-ATPase to determine ion transport, influences the transcriptome of macrophages and the ileum is unknown. Here compare transcript expression in bone marrow-derived macrophages and isolated ileum from mice deficient in GPR35 (knockout) with wild type mice by bulk RNA sequencing.
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Paper (PMID 40121360) ↗
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