GEO series
RNA-seq analysis of T-ALL cells following FTO or ELK3 silencing
GSE253269
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2025/04/02
GPL24676
Summary
FTO serves as one of the demethylases for RNA N (6)-methyladenosine (m6A). ELK3 is responsible for encoding a member within the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. To elucidate the roles and mechanisms of FTO and ELK3 in human T-cell acute lymphoblastic leukemia (T-ALL), we conducted RNA-seq analyses in KOPTK1 or CUTLL1 T-ALL cells following the silencing of FTO or ELK3
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Paper (PMID 40435251) ↗
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