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Bone morphogenetic protein increases tau phosphorylation and secretion in tauopathies in an APOE dependent manner

GSE253647 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2025/01/02 Platform GPL20301
Summary
To investigate the contribution of APOE genotype on neuronal transcription of key Alzheimer and BMP-relevant genes
Published in
Inhibition of Bone Morphogenetic Protein Signaling Prevents Tau Pathology in iPSC Derived Neurons and PS19 Mice
Affaneh A, Linden AK, Tunc-Ozcan E et al. · Annals of neurology 2025 · PMID 39644182 · doi:10.1002/ana.27149
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Direct links to NCBI, no account and no request form: the whole study as GSE253647_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1066402 and SRA study SRP484589. Searching any of these in the dataset finder brings you back here.

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