Tissue RNAsSeq of germ-free IL10KO versus WT mice in the presence or absence of human gut microbes
RNA-seq (gene expression) · mouse · 108 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 108 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasisImmunity · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE253945_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1067732 and SRA study SRP485303. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 108 more — browse all 108 samples with per-sample file links →
- GSE266466 Comparison of Ribosomal RNA profiles in mouse skeletal muscle in the presence and absence of the RNA binding portein HuR 56 samples shares presence, absence
- GSE266586 RNA-seq in murine LSKs after Cux1 and/or Ezh2 loss, in the presence or absence of the DNA damaging agent N-ethyl-N-nitrosourea 39 samples shares presence, absence
- GSE254211 Analysis of different mouse P14 CD8+T cell subset gene signatures in presence and absence of Tim-3+ Treg during LCMV CL13 infection 18 samples shares presence, absence
- GSE284043 RNAseq for peritoneal macrophages phagocytosing E.coli in the absence or presence of retinoic acid 16 samples shares presence, absence
- GSE249265 Transcriptomics of BMDM treated with PTEN in the presence or absence of STAT1 inhibitors 16 samples shares presence, absence
- GSE155132 Transcriptomic analysis of monocytes stimulated with M-CSF in the presence or absence of PFM037 or TNF or TNF +PFM037 16 samples shares presence, absence
- GSE227209 Single cell RNAseq of murine dendritic cells in presence or absence of Il13ra1 2 samples shares presence, absence
- GSE50097 Effect of Amphiregulin on global gene expression in injured skeletal muscle in the presence or absence of CD4+Foxp3+ regulatory T cells (Tregs). 12 samples shares presence, absence
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.