GEO series
Transcriptomes across seven brain regions from mouse model of anxiety
GSE254448
Mus musculus
Expression profiling by high throughput sequencing
10 samples
2025/02/25
GPL17021
Summary
Anxiety disorders are highly heterogeneous diseases. The molecular mechanisms underlying multi-brain region origin and sex dimorphism remain largely unknown. Herein, by leveraging large-scale transcriptomes across seven brain regions from mouse model of anxiety and extensive experiments at the molecular, synapse activity, and behavior levels, we dissected brain region- and sex-specific gene networks and identified critical sex-specific mediators of anxiety susceptibility.
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Paper (PMID 38990717) ↗
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