Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension.
Single-cell RNA-seq · human · 148 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Homo sapiens (human)
- Samples
- 148 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial HypertensionCirculation · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254617_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1071142 and SRA study SRP486906. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run PHBI_002 … PHBI_169 and carry no group information.
- GSM8047074 PHBI_002
- GSM8047075 PHBI_004
- GSM8047076 PHBI_005
- GSM8047077 PHBI_006
- GSM8047078 PHBI_008
- GSM8047079 PHBI_009
- GSM8047080 PHBI_010
- GSM8047081 PHBI_011
- GSM8047082 PHBI_013
- GSM8047083 PHBI_014
- GSM8047084 PHBI_015
- GSM8047085 PHBI_016
- GSM8047086 PHBI_017
- GSM8047087 PHBI_018
- GSM8047088 PHBI_019
- GSM8047089 PHBI_020
- GSM8047090 PHBI_021
- GSM8047091 PHBI_022
- GSM8047092 PHBI_023
- GSM8047093 PHBI_024
- GSM8047094 PHBI_025
- GSM8047095 PHBI_026
- GSM8047096 PHBI_027
- GSM8047097 PHBI_028
- GSM8047098 PHBI_029
- GSM8047099 PHBI_030
- GSM8047100 PHBI_031
- GSM8047101 PHBI_032
- GSM8047102 PHBI_033
- GSM8047103 PHBI_035
- GSM8047104 PHBI_037
- GSM8047105 PHBI_038
- GSM8047106 PHBI_039
- GSM8047107 PHBI_040
- GSM8047108 PHBI_041
- GSM8047109 PHBI_042
- GSM8047110 PHBI_043
- GSM8047111 PHBI_044
- GSM8047112 PHBI_045
- GSM8047113 PHBI_046
+ 108 more — browse all 148 samples with per-sample file links →
- GSE303084 Pressure Points: Endothelial Responses to Hemodynamic Stress in Health and Pulmonary Arterial Hypertension 72 samples shares hypertension, pulmonary, arterial
- GSE208592 Characterization of DNA methylation changes associated with lung and right ventricle dysfunction in pulmonary hypertension 33 samples shares hypertension, pulmonary, lung
- GSE244781 Molecular changes implicate angiogenesis and arterial remodeling in systemic sclerosis-associated and idiopathic pulmonary hypertension 33 samples shares hypertension, pulmonary, arterial
- GSE263226 Unravelling AURKB as a potential therapeutic target in pulmonary arterial hypertension using integrated transcriptomic analysis and pre-clinical studies 31 samples shares hypertension, pulmonary, arterial
- GSE272776 Integration of transcriptomics, proteomics, phosphoproteomics analysis for characterization of pulmonary arterial hypertension in Chinese people 16 samples shares hypertension, pulmonary, arterial
- GSE150910 RNA-Sequencing of Chronic hypersensitivity pneumonitis compared with Idiopathic Pulmonary Fibrosis and Control Lung 288 samples shares pulmonary, lung
- GSE310058 Single-nucleus transcriptomic profiling of human lung tissue in chronic obstructive pulmonary disease (COPD) [snRNA-seq] 149 samples shares pulmonary, lung
- GSE325715 Gene expression in patients with pulmonary hypertension due to valve heart disease 146 samples shares hypertension, pulmonary
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.