Multidimensional analysis of patient-matched primary and recurrent glioblastoma identifies microglial FCGR1A (CD64) and other FCGRs as contributors of tumor recurrence
Expression microarray · human · 147 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Topic
- GlioblastomaThis series is part of our curated briefing on it.
- Samples
- 147 samples: 126 distinct titles, 17 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
- Paper
- Multidimensional analysis of matched primary and recurrent glioblastoma identifies contributors to tumor recurrence influencing time to relapseJournal of neuropathology and experimental neurology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254875_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA1072122 and SRA study SRP488905. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 147 sample titles: 126 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8034904 Control_1
- GSM8034905 195_primary_CD64_long_Tala_001
- GSM8034906 195_primary_GFAP_long_Tala_002
- GSM8034907 195_recurrent_CD64_long_Tala_003
- GSM8034908 195_recurrent_GFAP_long_Tala_004
- GSM8034909 356_primary_CD64_short_Tala_005
- GSM8034910 356_primary_GFAP_short_Tala_005
- GSM8034911 282_primary_CD64_long_Tala_006
- GSM8034912 282_primary_GFAP_long_Tala_006
- GSM8034913 182_primary_CD64_short_Tala_007
- GSM8034914 182_primary_GFAP_short_Tala_008
- GSM8034915 185_primary_CD64_short_Tala_009
- GSM8034916 185_recurrent_CD64_short_Tala_010
- GSM8034917 185_recurrent_GFAP_short_Tala_010
- GSM8034918 185_recurrent_GFAP_short_Tala_011
- GSM8034919 417_primary_CD64_short_Tala_012
- GSM8034920 417_primary_CD64_short_Tala_013
- GSM8034921 417_primary_GFAP_short_Tala_014
- GSM8034922 417_recurrent_CD64_short_Tala_015
- GSM8034923 417_recurrent_GFAP_short_Tala_016
- GSM8034924 38_primary_CD64_long_Tala_017
- GSM8034925 38_primary_GFAP_long_Tala_017
- GSM8034926 38_recurrent_CD64_long_Tala_018
- GSM8034927 38_recurrent_GFAP_long_Tala_018
- GSM8034928 94_primary_CD64_long_Tala_019
- GSM8034929 94_primary_GFAP_long_Tala_019
- GSM8034930 94_recurrent_CD64_long_Tala_020
- GSM8034931 94_recurrent_GFAP_long_Tala_020
- GSM8034932 291_primary_GFAP_long_Tala_021
- GSM8034933 599_recurrent_CD64_short_Tala_022
- GSM8034934 599_recurrent_GFAP_short_Tala_022
- GSM8034935 599_primary_CD64_short_Tala_023
- GSM8034936 599_primary_GFAP_short_Tala_023
- GSM8034937 608_primary_CD64_long_Tala_024
- GSM8034938 608_primary_GFAP_long_Tala_024
- GSM8034939 182_recurrent_CD64_short_Tala_025
- GSM8034940 182_recurrent_GFAP_short_Tala_025
- GSM8034941 Copntrol_2
- GSM8034942 195_primary_GFAP_long_TalaSlide1Again_001
- GSM8034943 195_primary_GFAP_long_TalaSlide1Again_002
+ 107 more — browse all 147 samples with per-sample file links →
- GSE13041 Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age 267 samples same disease briefing · shares glioblastoma, identifies
- GSE107560 Ivy Glioblastoma Atlas Project 305 samples same disease briefing · shares glioblastoma
- GSE10878 Integrative Genome-wide Analysis of Glioblastoma. 60 samples same disease briefing · shares glioblastoma
- GSE112650 SOX4/11 Enhances NGN2 Reprogramming Glioblastoma Cells into Neuron Cells by Modulating RhoA and CDC42/RAC1 Pathway Activity 30 samples same disease briefing · shares glioblastoma
- GSE112648 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 18 samples same disease briefing · shares glioblastoma
- GSE112645 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 12 samples same disease briefing · shares glioblastoma
- GSE115459 Exosome-transmitted RVT1 from reactive astrocytes promotes recurrence glioblastoma proliferation 9 samples same disease briefing · shares glioblastoma
- GSE131928 single cell RNA-seq analysis of adult and paediatric IDH-wildtype Glioblastomas 2 samples same disease briefing · shares glioblastoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.