← BioTransfer GEO Dataset Finder
GEO series

Effect of STN1 knockdown on gene expression of PDAC cell lines

GSE254968 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/31 Platform GPL20795
Summary
We aimed to elucidate the mechanistic involvement of STN1 in facilitating the metastatic processes of PDAC. Utilizing RNA-seq profiling, we observed a substantial downregulation of the EMT pathway in PANC-1 cells with stable STN1 knockdown
Published in
STN1 facilitates metastasis by promoting transcription of EMT-activator ZEB1 in pancreatic cancer
Dong D, Zhou Z, Zhu M et al. · Nature communications 2025 · PMID 40841373 · doi:10.1038/s41467-025-63083-0
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE254968_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1072721 and SRA study SRP487817. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.