Transcriptome Analysis of Human Cancer Cells with Depleted or Overexpressed STELLA Proteins [RNA-seq]
RNA-seq (gene expression) · human · 51 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 51 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapyNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE255105_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1073525 and SRA study SRP488281. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 51 more — browse all 51 samples with per-sample file links →
- GSE228088 RNA-seq of Monocyte-derived Macrophages and Hepatic Stellate Cell Activation after 72hr 28 samples shares stella, rna-seq
- GSE253493 RNA-Seq experiment of primary hepatic stellate cells (HSCs) and LX-2 cell line treated with TGFb 12 samples shares stella, rna-seq
- GSE290282 Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection [RNA-Seq] 92 samples shares proteins, rna-seq
- GSE287297 Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia [RNA-seq] 70 samples shares proteins, rna-seq
- GSE315341 Overcoming Menin inhibitor resistance in AML cells with combinations including BET proteins and dual BRG1/BRM inhibitor [RNA-seq] 60 samples shares proteins, rna-seq
- GSE268092 TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance and general RNA synthesis in translocation renal cell carcinoma. [RNA-seq] 36 samples shares proteins, rna-seq
- GSE311641 Oncofetal RNA-binding proteins IGF2BP suppress innate immune signaling pathways in leukemia stem cells [RNA-seq] 32 samples shares proteins, rna-seq
- GSE306946 RNA-SEQ of HRECs depleted with Norrin/beta-catenin signaling components or KIF11 or PRDX1 27 samples shares depleted, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.