GEO series
Changes in chromatin accessibility in intratumoral CD8+ T cell subsets between young and aged TME
GSE255230
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
38 samples
2024/03/14
GPL32159GPL19057
Summary
Here, we present genome-wide comparisons of chromatin accessibility from endogenous CD8+ T cells and transferred OT-1 CD8+ T cells in young vs. aged B16-OVA tumors using ATAC-seq. This ATAC-seq dataset includes three different intratumoral CD8+ T cell subsets, such as TProg: Slamf6+Tim-3-, TTerm: Slamf6-Tim-3+, and TTAD: Slamf6-Tim-3-, as well as naive CD8+ T cells from spleens.
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Paper (PMID 38745085) ↗
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