Spatial transcriptomics landscape for liver from patients with metabolic dysfunction-associated steatohepatitis (MASH)
Spatial transcriptomics · human · 72 samples
- What it is
- Spatial transcriptomicsGene activity measured with its position in a tissue section.
- Organism
- Homo sapiens (human)
- Samples
- 72 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE255312_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Spatial studies usually ship Space Ranger style folders (count matrix plus tissue images). Look for them among the supplementary files.
Also filed as BioProject PRJNA1074478. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 72 more — browse all 72 samples with per-sample file links →
- GSE309979 GeoMx GeoMx-DSP Toxic Lipid-induced Epigenetic Activation of ICAM1 in Liver Sinusoidal Endothelium Regulates Myeloid-Driven Fibro-inflammatory Response in MASH 217 samples shares mash, liver
- GSE289173 Single-cell eQTL analysis identifies genetic variation underlying metabolic dysfunction-associated steatohepatitis 48 samples shares dysfunction-associated, steatohepatitis
- GSE244832 Multi-Modal Comparison of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease 36 samples shares dysfunction-associated, liver
- GSE333851 Spatial Glyco-Codes Define Human Liver Pathology and Progression 32 samples shares spatial, liver
- GSE268518 Duodenal-derived organoids from MASH patients exhibit altered digestive homeostasis. 39 samples shares mash
- GSE235714 Immune-Epithelial Interactions and Tissue Remodeling in the Inflammatory Respiratory Nasal Tract [NanoString GeoMx spatial transcriptomics] 40 samples shares spatial
- GSE250521 A Spatially Resolved Transcriptome Landscape during Thyroid Cancer Progression 25 samples shares spatial
- GSE228360 Spatial and single cell transcriptomics reveals cellular crosstalk changes in ileal Crohn’s disease during inflammation 24 samples shares spatial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.