GEO series
Multiple layers of innate immune response antagonism of SARS-CoV-2
GSE255483
Mus musculus
Expression profiling by high throughput sequencing
16 samples
2026/06/03
GPL24247
Summary
Analysis of immune cells in lungs from infected mice with either WT SARS-CoV-2, the NSP1 or the NSP15 mutant or mock-infection by single-cell RNA-seq identified 15 populations of major myeloid and lymphoid cells with changes in the pattern of their activation associated with viral infection. The effects of mutations in NSP1 or NSP15 on these responses suggested different immunosuppressive mechanisms of the two viral proteins.
Download
NCBI GEO page ↗
Paper (PMID 42160380) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
mouse RNA-seq datasets →
Similar datasets
- GSE292862 Modelling mouse embryogenesis from chemically induced totipotent stem cells 22 samples
- GSE185862 A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation 95 samples
- GSE334940 Tissue nanotransfection-mediated induction of neurogenic programs promotes myoprotective responses in denervated skeletal muscle 15 samples
- GSE304862 Semaglutide and exercise synergy in obesity: preserving muscle mass and uncovering organ crosstalk 209 samples
- GSE343043 Disease context dictates the cellular targets of IL-17 in inflammatory skin disease 29 samples
- GSE341948 Multi-tissue transcriptomic landscape reveals synergistic mechanisms of exercise and GLP-1 agonist in ameliorating diabetic phenotypes in db/db mice 12 samples
- GSE293315 MRPGRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis Dataset 2 35 samples
- GSE321707 Characterization of TLR signaling in Ticam2-/- macrophages 30 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.