GEO series
Impaired T cell and neoantigen retention in time serial analysis of lung cancer patients treated with TIL cell therapy
GSE255549
Homo sapiens
Expression profiling by high throughput sequencing
36 samples
2024/12/19
GPL30173GPL18573
Summary
We mapped TIL clones into individual transcriptomes and found that neoantigen-reactive clonotypes expressed a dysfunctional program and lacked stem-like features among patients who lacked clinical benefit.
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Paper (PMID 40341231) ↗
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