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Gene expression and T cell repertoire profile at single cell level of peripheral blood T cells after treatment with a personalized neoantigen vaccine (GNOS-PV02) and Pembrolizumab for advanced hepatocellular carcinoma.

GSE255830 Homo sapiens Expression profiling by high throughput sequencing; Other 8 samples Submitted 2024/05/17 Platform GPL24676
Summary
To further characterize the T cell response to the neoantigen vaccine, we performed single-cell RNA and T cell receptor (scRNA/TCR-seq) of peripheral blood T cells at the 12-week post-vaccination time point.
Published in
Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial
Yarchoan M, Gane EJ, Marron TU et al. · Nature medicine 2024 · PMID 38584166 · doi:10.1038/s41591-024-02894-y
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Also filed as BioProject PRJNA1076640. Searching any of these in the dataset finder brings you back here.

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