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Effect of EGCG to multiple myeloma MM.1S cells on gene expression

GSE256433 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/02/23 Platform GPL24676
Summary
Epigallocatechin-3-gallate (EGCG) is the most plentiful polyphenol in green tea and has antiviral, antioxidant, anti-aging, anti-inflammatory, and neuroprotective effects . Studies have shown that EGCG can inhibit a diversity of biological processes of tumor progression, including cell proliferation, invasion, metastasis, and angiogenesis, and can also induce apoptosis and cell cycle arrest. In order to investigate the role of EGCG in multiple myeloma (MM), we carried out this study. We found that EGCG could inhibit myeloma cell activity and promote myeloma cell apoptosis. To further explore the mechanism of EGCG promoting apoptosis in myeloma cells, cells were treated with EGCG and subjected to RNA sequencing.
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Also filed as BioProject PRJNA1079665 and SRA study SRP491316. Searching any of these in the dataset finder brings you back here.

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