PABPC1 SUMOylation enhances cell survival by promoting mitophagy through stabilizing U-rich mRNAs within stress granules
Non-coding RNA profiling · human · 36 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 36 samples: 18 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PABPC1 SUMOylation enhances cell survival by promoting mitophagy through stabilizing U-rich mRNAs within stress granulesNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260511_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1081908 and SRA study SRP492403. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 36 samples.
How we read this: 18 replicated groups read from 36 sample titles; they account for 36 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8118596 0h-WT-repeat1 0h-WT-repeat
- GSM8118597 0h-WT-repeat2 0h-WT-repeat
- GSM8118598 3h-WT-repeat1 3h-WT-repeat
- GSM8118599 3h-WT-repeat2 3h-WT-repeat
- GSM8118600 6h-WT-repeat1 6h-WT-repeat
- GSM8118601 6h-WT-repeat2 6h-WT-repeat
- GSM8118602 AS-3h-WT-repeat1 AS-3h-WT-repeat
- GSM8118603 AS-3h-WT-repeat2 AS-3h-WT-repeat
- GSM8118604 AS-6h-WT-repeat1 AS-6h-WT-repeat
- GSM8118605 AS-6h-WT-repeat2 AS-6h-WT-repeat
- GSM8118606 0h-K512R-repeat1 0h-K512R-repeat
- GSM8118607 0h-K512R-repeat2 0h-K512R-repeat
- GSM8118608 3h-K512R-repeat1 3h-K512R-repeat
- GSM8118609 3h-K512R-repeat2 3h-K512R-repeat
- GSM8118610 6h-K512R-repeat1 6h-K512R-repeat
- GSM8118611 6h-K512R-repeat2 6h-K512R-repeat
- GSM8118612 AS-3h-K512R-repeat1 AS-3h-K512R-repeat
- GSM8118613 AS-3h-K512R-repeat2 AS-3h-K512R-repeat
- GSM8118614 AS-6h-K512R-repeat1 AS-6h-K512R-repeat
- GSM8118615 AS-6h-K512R-repeat2 AS-6h-K512R-repeat
- GSM8118626 WT IP rep1 WT IP
- GSM8118627 WT IP rep2 WT IP
- GSM8118628 WT input rep1 WT input
- GSM8118629 WT input rep2 WT input
- GSM8118630 WT-AS IP rep1 WT-AS IP
- GSM8118631 WT-AS IP rep2 WT-AS IP
- GSM8118632 WT-AS input rep1 WT-AS input
- GSM8118633 WT-AS input rep2 WT-AS input
- GSM8118634 K512R IP rep1 K512R IP
- GSM8118635 K512R IP rep2 K512R IP
- GSM8118636 K512R input rep1 K512R input
- GSM8118637 K512R input rep2 K512R input
- GSM8118638 K512R-AS IP rep1 K512R-AS IP
- GSM8118639 K512R-AS IP rep2 K512R-AS IP
- GSM8118640 K512R-AS input rep1 K512R-AS input
- GSM8118641 K512R-AS input rep2 K512R-AS input
- GSE260508 PABPC1 SUMOylation enhances cell survival by promoting mitophagy through stabilizing U-rich mRNAs within stress granules (4sU-Seq) 20 samples shares pabpc1, sumoylation, stabilizing, promoting, mitophagy, enhances, survival, granules
- GSE329512 SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry 19 samples shares sumoylation, enhances
- GSE329305 SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry [ChIP_WT-vs-CW-dTAG] 14 samples shares sumoylation, enhances
- GSE329304 SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry [ChIP_gUHRF1-and-WT-vs-RFTS] 13 samples shares sumoylation, enhances
- GSE224179 MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD 12 samples shares promoting, survival
- GSE304059 Mechanism study of RBX1 promoting renal clear cell carcinoma invasion, immune suppression, and sunitinib resistance 614 samples shares promoting
- GSE199913 KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage 231 samples shares promoting
- GSE279152 The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release 211 samples shares promoting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.