GEO series
Chromatin profiling following SWI/SNF inhibition in H295R or HEK 293T cells [ChIP-seq]
GSE260867
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
25 samples
2025/07/21
GPL18573
Summary
To assess the genome-wide effect of acute SWI/SNF inhibition on SF-1/β-catenin chromatin binding, we treated H295R or HEK 293T cells with 1 µM of SWI/SNF inhibitor BRM014 or DMSO vehicle control for 1 hour and performed ChIP-seq. Pronounced loss of chromatin occupancy was observed for SF-1 and β-catenin at enhancer sites bound by ARID1A-containing cBAF complexes.
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Paper (PMID 40695292) ↗
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