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Hepatic GPNMB aggravates NASH through binding to RYK [RNA-Seq]

GSE260956 Mus musculus; Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/12/03 Platform GPL30209Platform GPL30215
Summary
The goals of this study are to define the moelcular events in NASH and to determine the role of GPNMB and RYK in NASH development
Published in
RYK is a GPNMB receptor that drives MASH
Xi Y, Zeng W, Luo J et al. · Nature 2026 · PMID 41708863 · doi:10.1038/s41586-026-10160-z
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Also filed as BioProject PRJNA1084732 and SRA study SRP493598. Searching any of these in the dataset finder brings you back here.

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