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Single-cell characterization of differentiated HepaRG cells

GSE261025 Homo sapiens Expression profiling by high throughput sequencing 5 samples Submitted 2024/08/29 Platform GPL24676
Summary
We used scRNA-seq to characterise the differentiation status of HepaRG cells after applying standard differentiation protocols on these cells. For downstream Perturb-seq we also characterised two cell lines of different genotype; Wt and cells transduced with dCas9-KRAB.
Published in
A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes
Saliba-Gustafsson P, Justesen JM, Ranta A et al. · Hepatology (Baltimore, Md.) 2025 · PMID 39190705 · doi:10.1097/HEP.0000000000001066
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Also filed as BioProject PRJNA1084840 and SRA study SRP493696. Searching any of these in the dataset finder brings you back here.

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