GEO series
Transcriptomic analysis of Omicron Pseudovirus(PsV)-infected HSPCs(hematopoietic stem and progenitor cells)
GSE261419
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/02/09
GPL24676
Summary
We have developed a SARS-CoV-2 PsV system that expresses the spike protein on the viral surface and carries spike protein genomic sequences, enabling this pseudovirus to activate infection signaling pathways through ACE2 and stimulate intracellular spike protein gene expression. To understand the impact of SARS-CoV-2 on hematopoietic system, we infected heman HSPCs with Omicron PsV and analyzed changes in transcriptome
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Paper (PMID 40025168) ↗
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