PRMT5 promotes growth of pediatric high grade glioma.
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 50 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 50 samples: 40 distinct titles, 5 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PRMT5 Maintains Tumor Stem Cells to Promote Pediatric High-Grade Glioma TumorigenesisMolecular cancer research : MCR · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE261514_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1087354 and SRA study SRP495044. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 50 sample titles: 40 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8145498 BT245 cells transduced with control shRNA SHC202
- GSM8145499 BT245 cells transduced with PRMT targeting shRNA TRCN0000381130
- GSM8145500 BT245 cells transduced with PRMT targeting shRNA TRCN0000303446
- GSM8145501 BT245 cells transduced with PRMT targeting shRNA TRCN0000379612
- GSM8145502 DIPG4 cells transduced with control shRNA SHC202
- GSM8145503 DIPG4 cells transduced with PRMT targeting shRNA TRCN0000381130
- GSM8145504 DIPG4 cells transduced with PRMT targeting shRNA TRCN0000303446
- GSM8145505 DIPG4 cells transduced with PRMT targeting shRNA TRCN0000379612
- GSM8145506 DIPG7 cells transduced with control shRNA SHC202
- GSM8145507 DIPG7 cells transduced with PRMT targeting shRNA TRCN0000381130
- GSM8145508 DIPG7 cells transduced with PRMT targeting shRNA TRCN0000303446
- GSM8145509 DIPG7 cells transduced with PRMT targeting shRNA TRCN0000379612
- GSM8145510 DIPG13* cells transduced with control shRNA SHC202
- GSM8145511 DIPG13* cells transduced with PRMT targeting shRNA TRCN0000381130
- GSM8145512 DIPG13* cells transduced with PRMT targeting shRNA TRCN0000303446
- GSM8145513 DIPG13* cells transduced with PRMT targeting shRNA TRCN0000379612
- GSM8145514 GBM1 cells transduced with control shRNA SHC202
- GSM8145515 GBM1 cells transduced with PRMT targeting shRNA TRCN0000381130
- GSM8145516 GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446
- GSM8145517 GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612
- GSM8145518 BT245 cells transduced with control shRNA SHC202 - input sample
- GSM8145519 BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - input sample
- GSM8145520 BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - input sample
- GSM8145521 GBM1 cells transduced with control shRNA SHC202 - input sample
- GSM8145522 GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - input sample
- GSM8145523 GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - input sample
- GSM8145524 BT245 cells transduced with control shRNA SHC202 - IgG immunoprecipitation
- GSM8145525 BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - IgG immunoprecipitation
- GSM8145526 BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - IgG immunoprecipitation
- GSM8145527 GBM1 cells transduced with control shRNA SHC202 - IgG immunoprecipitation
- GSM8145528 GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 - IgG immunoprecipitation
- GSM8145529 GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - IgG immunoprecipitation
- GSM8145530 BT245 cells transduced with control shRNA SHC202 - H3K4me3 immunoprecipitation
- GSM8145531 BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - H3K4me3 immunoprecipitation
- GSM8145532 BT245 cells transduced with PRMT targeting shRNA TRCN0000303446 - H3K4me3 immunoprecipitation
- GSM8145533 GBM1 cells transduced with control shRNA SHC202 - H3K4me3 immunoprecipitation
- GSM8145534 GBM1 cells transduced with PRMT targeting shRNA TRCN0000303446 -H3K4me3 immunoprecipitation
- GSM8145535 GBM1 cells transduced with PRMT targeting shRNA TRCN0000379612 - H3K4me3 immunoprecipitation
- GSM8145536 BT245 cells transduced with control shRNA SHC202 - H3K27me3 immunoprecipitation
- GSM8145537 BT245 cells transduced with PRMT targeting shRNA TRCN0000381130 - H3K27me3 immunoprecipitation
+ 10 more — browse all 50 samples with per-sample file links →
- GSE292623 A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma 18 samples shares pediatric, glioma, grade
- GSE282004 Tumor Exosome-transmitted LncRNA CATED Promotes Platinum-resistant in High-grade Serous Ovarian Cancer 17 samples shares promotes, grade
- GSE300244 Boosting CAR T-cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas 42 samples shares pediatric, glioma
- GSE269555 Targeting the oncohistone-ASCL1 axis disrupts plasticity and suppresses pediatric gliomas [CUT&RUN] 39 samples shares pediatric, glioma
- GSE281320 DNMT3B promotes neuroblastoma growth and survival, and its inhibition demonstrates antitumor effects. 6 samples shares promotes, growth
- GSE254521 Epigenetic priming promotes acquisition of TKI resistance and oncogene amplification in human lung cancer 146 samples shares promotes
- GSE218269 CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release 100 samples shares promotes
- GSE282423 Imaging-based drug screening combined with moleuclar profiling identifies signatures and drivers of therapy resistance in pediatric AML [RNA-seq] 28 samples shares pediatric
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.