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Extended culture of 2D gastruloids to model human mesoderm development

GSE262081 Homo sapiens Expression profiling by high throughput sequencing 5 samples Submitted 2025/01/15 Platform GPL24676
Summary
Micropatterned human pluripotent stem cells (hPSCs) treated with BMP4, known as a 2D gastruloid, are among the most widely used stem cell models for human gastrulation. Due to its simplicity and reproducibility, this system is ideal for high throughput quantitative studies of tissue patterning and has led to many insights into the mechanisms of mammalian gastrulation. However, 2D gastruloids have only been studied up to 48h. Here we extended this system to 96h.
Published in
Extended culture of 2D gastruloids to model human mesoderm development
Chen B, Khan H, Yu Z et al. · bioRxiv : the preprint server for biology 2024 · PMID 38585971 · doi:10.1101/2024.03.21.585753
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Also filed as BioProject PRJNA1090137 and SRA study SRP496761. Searching any of these in the dataset finder brings you back here.

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