The chromatin accessibility landscape of mouse oocytes during configuration transition (CUT&Tag)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × h3k27me3_nsn vs 3 × h3k27me3_sn vs 2 × h3k4me3_nsn vs 2 × h3k4me3_snGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The chromatin accessibility landscape of mouse oocytes during configuration transitionCell proliferation · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262263_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1090928 and SRA study SRP497272. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8162166 h3k27me3_nsn_rep1 h3k27me3_nsn
- GSM8162167 h3k27me3_nsn_rep2 h3k27me3_nsn
- GSM8162168 h3k27me3_nsn_rep3 h3k27me3_nsn
- GSM8162169 h3k27me3_sn_rep1 h3k27me3_sn
- GSM8162170 h3k27me3_sn_rep2 h3k27me3_sn
- GSM8162171 h3k27me3_sn_rep3 h3k27me3_sn
- GSM8162172 h3k4me3_nsn_rep1 h3k4me3_nsn
- GSM8162173 h3k4me3_nsn_rep2 h3k4me3_nsn
- GSM8162174 h3k4me3_sn_rep1 h3k4me3_sn
- GSM8162175 h3k4me3_sn_rep2 h3k4me3_sn
- GSM8162176 nsn_input
- GSM8162177 sn_input
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares cut, transition, chromatin
- GSE255571 Chromatin remodeler CHD7 regulates neurogenic gene expression via controlling chromatin accessibility and modifications of histone marks H3K27me3 and H3K4me3 [Mouse CUT&Tag] 10 samples shares cut, accessibility, chromatin
- GSE305877 BLIMP1 shapes germinal center B-cell clonal diversity by gating chromatin accessibility during light-to-dark zone transition 18 samples shares accessibility, transition, chromatin
- GSE298418 MeCP2 stabilizes the glucocorticoid system in active chromatin regions [CUT&Tag] 63 samples shares cut, chromatin
- GSE274493 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis [CUT&Tag] 46 samples shares cut, chromatin
- GSE292333 H2AK119ub1-MLL2 counteraction underlies heritable H3K27me3 formation in oocytes [CATCH-seq and CUT&RUN] 44 samples shares cut, oocytes
- GSE274875 A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia [Cut & Run] 38 samples shares cut, chromatin
- GSE264229 Mapping the male mouse chromatin accessibility landscape by UUATAC-seq 33 samples shares accessibility, chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.