BCAT1 contributes to the developmentproliferation and leukemogenesis of TKI-resistant CML
RNA-seq (gene expression) · mouse · 2 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE262421_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1091685 and SRA study SRP497763. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE247299 BCAT1 regulates glioblastoma cell plasticity and contributes to immunosuppression 6 samples shares bcat1, contributes
- GSE267966 Effect of depletion of BCAT1 on gene expression during NOTCH1-dependent leukemia development in the mouse 15 samples shares bcat1
- GSE282215 BCAT1 activation reprograms branched-chain amino acids (BCAAs) metabolism and epigenetically promotes inflammation in diabetic retinopathy 9 samples shares bcat1
- GSE226644 The effect of bcCML leukemia progression on the bone marrow microenvironment 7 samples shares cml
- GSE227082 The effect of SLC6A6 Knock-down on bcCML leukemia 6 samples shares cml
- GSE305990 cmLumiOpto gene therapy in combination with chemotherapy to treat triple negative breast cancer. 4 samples shares cml
- GSE313892 CD276-DM1 Antibody drug conjugate with cmLumiOpto gene therapy to treat triple negative breast cancer. 4 samples shares cml
- GSE244876 BCAT1 drives cardiac fibrosis by promoting proline synthesis machinery 2 samples shares bcat1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.