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Gene expression profile of FACS sorted cranial neural crest cells from E12.5-E13.5 mouse embryonic head

GSE262468 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/10/29 Platform GPL24247
Summary
Craniofacial morphogenesis depends on complex cell fate decisions during the differentiation of post-migratory cranial neural crest cells. Molecular mechanisms of cell differentiation of mesenchymal cells to developing bones, cartilage, teeth, tongue, and other craniofacial tissues are still poorly understood. We performed single-cell transcriptomic analysis of craniofacial mesenchymal cells derived from cranial NCCs in mouse embryo. Using FACS sorting of Wnt1-Cre2 progeny, we carefully map the cell heterogeneity in the craniofacial region during the initial stages of bone and cartilage formation.
Published in
Single-cell transcriptomic resolution of osteogenesis during craniofacial morphogenesis
Hudacova E, Abaffy P, Kaplan MM et al. · Bone 2025 · PMID 39461490 · doi:10.1016/j.bone.2024.117297
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Also filed as BioProject PRJNA1091940 and SRA study SRP497885. Searching any of these in the dataset finder brings you back here.

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