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Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function

GSE262931 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2024/07/05 Platform GPL24676
Summary
We used bulk and single-cell ATAC-seq to measure chromatin accessibilty in human kidneys. This allowed us to define candidate cis-regulatory elements of each human kidney cell type and identify the role of podocyte and tubule regulatory elements in human kidney function.
Published in
Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function
Loeb GB, Kathail P, Shuai RW et al. · Nature genetics 2024 · PMID 39256582 · doi:10.1038/s41588-024-01904-6
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Also filed as BioProject PRJNA1094933 and SRA study SRP499048. Searching any of these in the dataset finder brings you back here.

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