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Transcriptomic changes in SUDHL6 cells upon treatment with S63845 in the presence or abscence of active caspases

GSE263183 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/04/24 Platform GPL24676
Summary
We identified a novel form of caspase-independent cell death (CICD) induced by BH3-mimetics. To characterize the transcriptional changes during CICD and compare these to apoptotic changes, we performed RNA Seq analysis on SUDHL6 lymphoma cells treated with the MCL1 inhibitor S63845 in the presence or abscence of the broad spectrum caspase inhibitor zVAD.fmk.
Published in
Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines
Yildirim N, Sarojam L, Smith VM et al. · Cell death & disease 2024 · PMID 38622118 · doi:10.1038/s41419-024-06652-3
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Also filed as BioProject PRJNA1096049 and SRA study SRP499621. Searching any of these in the dataset finder brings you back here.

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