Gene expression profiling of sorted primary human bronchial epithelial cell populations
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Tropism for ciliated cells is the dominant driver of influenza viral burst size in the human airwayProceedings of the National Academy of Sciences of the United States of America · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263356_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1010235 and SRA study SRP457312. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8190153 NHBE cells, basal population, rep A
- GSM8190154 NHBE cells, basal population, rep B
- GSM8190155 NHBE cells, basal population, rep C
- GSM8190156 NHBE cells, ciliated population, rep A
- GSM8190157 NHBE cells, ciliated population, rep B
- GSM8190158 NHBE cells, ciliated population, rep C
- GSM8190159 NHBE cells, CD66c+ other population, rep A
- GSM8190160 NHBE cells, CD66c+ other population, rep B
- GSM8190161 NHBE cells, CD66c+ other population, rep C
- GSM8190162 NHBE cells, secretory population, rep A
- GSM8190163 NHBE cells, secretory population, rep B
- GSM8190164 NHBE cells, secretory population, rep C
- GSM8190165 NHBE cells, triple negative population, rep A
- GSM8190166 NHBE cells, triple negative population, rep B
- GSM8190167 NHBE cells, triple negative population, rep C
- GSM8190168 NHBE cells, undifferentiated, rep A
- GSM8190169 NHBE cells, undifferentiated, rep B
- GSM8190170 NHBE cells, undifferentiated, rep C
- GSE327707 Sorted bulk RNA-seq profiling of human peripheral blood mononuclear cell populations across diverse in vitro immune stimuli 150 samples shares populations, sorted
- GSE315683 Transcriptional and proteome profiling of human bronchial epithelial cell BEAS-2B exposed to e-cigarette aerosol condensate 9 samples shares epithelial, bronchial
- GSE161245 Comparison of bronchial epithelial cells obtained by bronchoscopy from mild asthma patients, moderate asthma patients, severe asthma patients and healthy controls 55 samples shares epithelial, bronchial
- GSE272820 Multi-omics datasets for finer-scale dissection of chromatin architecture alterations in radiation induced malignant transformation of bronchial epithelial cells [Micro-C] 12 samples shares epithelial, bronchial
- GSE314342 Genome-scale perturb-seq in primary human CD4+ T cells reveals genes regulating T cell programs and human immune traits. 577 samples shares primary
- GSE205154 Bulk RNA-Seq gene expression data for 289 primary and metastatic pancreatic ductal adenocarcinoma (PDAC) tumor samples from FFPE blocks. 289 samples shares primary
- GSE316391 Chromatin accessibility and gene expression profiling of primary and metastatic ER+ breast cancer [RNA-seq] 32 samples shares primary
- GSE302095 Validation of bronchial airway gene expression associated with bronchiectasis in nasal epithelium 132 samples shares bronchial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.