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Integrated transcriptomic, epigenetic, and TCR clonality analysis of CD4⁺ Tm subsets in liver and lung during chronic GVHD in mice [ATAC-seq]

GSE263810 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2025/12/11 Platform GPL24247
Summary
Pathogenic CD4+ T cells perpetuate chronic tissue inflammation, but mechanisms remain largely undefined. Here, with transcriptome, epigenome, and clonal analysis, we compared CD4+Tm subsets among the liver and lung in the No GVHD and cGVHD recipients. Four CD4+Tm subsets identified with Ly108 versus CD69 expression were compared.
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Direct links to NCBI, no account and no request form: the whole study as GSE263810_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1099281 and SRA study SRP501296. Searching any of these in the dataset finder brings you back here.

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