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Chromatin accessibility landscapes across T-ALL

GSE263977 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 5 samples Submitted 2025/10/02 Platform GPL24676
Summary
Acute lymphoblastic leukemia (ALL) is the most common malignancy in pediatric patients and represents about a quarter of all pediatric malignancies. While transcriptional and DNA methylation profiling of these subtypes has been extensively examined, the accompanying chromatin landscape and corresponding gene regulatory repertoire is not well characterized for many ALL types. To better understand the ALL epigenome and gene regulatory network we mapped chromatin accessibility for T-ALL patient samples using assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) .
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Direct links to NCBI, no account and no request form: the whole study as GSE263977_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1100491 and SRA study SRP501826. Searching any of these in the dataset finder brings you back here.

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