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ChIP seq of CDK6-WT and CDK6-K43M in murine BCR-ABL(p185)+ pre/pro B-cells

GSE264219 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2024/06/30 Platform GPL17021
Summary
The aim of this experiment was to study the DNA interaction of a kinase-dead mutant of the cell cycle kinase CDK6 (CDK6-K43M) in a murine model of BCR-ABL driven leukemia.
Published in
CDK6 kinase inhibition unmasks metabolic dependencies in BCR::ABL1+ leukemia
Scheiblecker L, Klampfl T, Doma E et al. · Cell death & disease 2025 · PMID 39966356 · doi:10.1038/s41419-025-07434-1
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Direct links to NCBI, no account and no request form: the whole study as GSE264219_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1101496 and SRA study SRP502385. Searching any of these in the dataset finder brings you back here.

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