Single cell gene expression profile of peripheral whole blood cells from long COVID patients
Single-cell RNA-seq · human · 13 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 13 samples: 13 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapyScientific data · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE265753_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1104143 and SRA study SRP503784. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 13 sample titles: 13 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8228239 Multiplexing set 1, Whole transcriptome analysis library (WTA), scRNAseq
- GSM8228240 Multiplexing set 1, Sample Tag library (ST), scRNAseq
- GSM8228241 Multiplexing set 2, Whole transcriptome analysis and Sample Tag (ST) libraries, scRNAseq
- GSM8228242 Multiplexing set 3, Sample Tag library (ST), scRNAseq
- GSM8228243 Multiplexing set 3, Whole transcriptome analysis library (WTA), scRNAseq
- GSM8228244 Multiplexing set 4, Sample Tag library (ST), scRNAseq
- GSM8228245 Multiplexing set 4, Whole transcriptome analysis library (WTA), scRNAseq
- GSM8228246 Multiplexing set 5, Sample Tag library (ST), scRNAseq
- GSM8228247 Multiplexing set 5, Whole transcriptome analysis library (WTA), scRNAseq
- GSM8228248 Multiplexing set 6, Sample Tag library (ST), scRNAseq
- GSM8228249 Multiplexing set 6, Whole transcriptome analysis library (WTA), scRNAseq
- GSM8228250 Multiplexing set 7, Sample Tag library (ST), scRNAseq
- GSM8228251 Multiplexing set 7, Whole transcriptome analysis library (WTA), scRNAseq
- GSE267625 Whole blood transcriptome in long-COVID patients reveals association with lung function and immune response 111 samples shares covid, whole, blood, long
- GSE207625 RNA Sequencing Analysis of Peripheral Blood Mononuclear Cells Associated with COVID-19 Deterioration 12 samples shares covid, peripheral, blood
- GSE243219 Comparative Analysis of Host Responses Between Sepsis and COVID-19: A Prospective Observational Study of Whole Blood Transcriptome 144 samples shares covid, whole, blood
- GSE288704 Whole transcriptome analysis of unmutated sporadic ALS patients’ peripheral blood reveals phenotype-specific gene expression signature 66 samples shares peripheral, whole, blood
- GSE310095 Whole Blood Transcriptomics Differentiates Circulating Gene Expression Between Coronary Artery Disease and Peripheral Artery Disease 71 samples shares peripheral, whole, blood
- GSE300475 Single cell RNA sequencing for longitudinal human peripheral blood from HR+ breast cancer patients treated with immunotherapy 32 samples shares peripheral, blood, long
- GSE254176 Dynamic changes of immune cells in systemic lupus erythematosus with nephritis using longitudinal peripheral blood single-cell RNA-seq 57 samples shares peripheral, blood, long
- GSE196198 Longitudinal single-cell multiomics data for different severity of COVID-19 100 samples shares covid, long
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.