Remodeling of Il4-Il13-Il5 locus underlies selective gene expression (mRNA-Seq)
RNA-seq (gene expression) · mouse · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 13 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Remodeling of Il4-Il13-Il5 locus underlies selective gene expressionNature immunology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE266347_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1106808 and SRA study SRP505185. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 13 sample titles: 13 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8245443 HN_BL_179_invitroTh2_Nostim_4h_rep1
- GSM8245444 HN_BL_180_invitroTh2_Nostim_4h_rep2
- GSM8245445 HN_BL_181_invitroTh2_CD3_CD28_4h_rep1
- GSM8245446 HN_BL_182_invitroTh2_CD3_CD28_4h_rep2
- GSM8245447 HN_BL_183_human_naiveTh_donor1
- GSM8245448 HN_BL_184_human_naiveTh_donor2
- GSM8245449 HN_BL_185_human_naiveTh_donor3
- GSM8245450 HN_BL_186_human_invitroTh2_nostim_donor1
- GSM8245451 HN_BL_187_human_invitroTh2_nostim_donor2
- GSM8245452 HN_BL_188_human_invitroTh2_nostim_donor3
- GSM8245453 HN_BL_189_human_invitroTh2_PI_4h_donor1
- GSM8245454 HN_BL_190_human_invitroTh2_PI_4h_donor2
- GSM8245455 HN_BL_191_human_invitroTh2_PI_4h_donor3
- GSE272831 Adipogenesis, lipolysis, and extracellular matrix remodeling are early modulated by a triterpene-enriched natural extract in a mouse cell line and primary human adipocytes 40 samples shares remodeling
- GSE289991 Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartum [bulk RNA-seq] 294 samples shares remodeling
- GSE289109 Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptic remodeling in the inflamed brain [snRNA-Seq] 20 samples shares remodeling
- GSE306773 Myocardial Reprogramming by HMGN1 Underlies Heart Defects in Trisomy 21 [scRNA-seq] 29 samples shares underlies
- GSE212837 An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in non-alcoholic steatohepatitis 20 samples shares underlies
- GSE291268 Cardiac Radiotherapy-Induced Epigenetic Memory Underlies Electrophysiologic and Metabolic Reprogramming [ATAC-seq] 50 samples shares underlies
- GSE268567 Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability 30 samples shares selective
- GSE325898 Selective Translation of ZNF281 as Part of the Integrated Stress Response System has Therapeutic Relevance for Cardio-Oncology 18 samples shares selective
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.