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Flow-Mediated Modulation of the Endothelial Cell Lipidome

GSE266437 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/07/01 Platform GPL21290
Summary
The luminal surface of the endothelium is exposed to dynamic blood flow patterns that are known to affect endothelial cell phenotype. In this study, human aortic endothelial cells (HAECs) were exposed to unidirectional laminar flow (20 dynes/cm2) or disturbed flow (±4 dynes/cm2, 2 Hz) for 48 hrs and then subjected to RNA sequencing. The sequencing data was used to analyze changes in endothelial cell gene expression and pathways associated with lipid metabolism.
Published in
Flow-mediated modulation of the endothelial cell lipidome
Hong SG, Kennelly JP, Williams KJ et al. · Frontiers in physiology 2024 · PMID 39119214 · doi:10.3389/fphys.2024.1431847
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Also filed as BioProject PRJNA1107180 and SRA study SRP505468. Searching any of these in the dataset finder brings you back here.

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